Why give donepezil at night

Daily Med: Aricept donepezil. NLM website. Accessed May 7, Impact of nighttime donepezil administration on sleep in the older adult population: A retrospective study. Mental Health Clinician: September , Vol. Singer M, et al. Nightmares in patients with Alzheimer's disease caused by donepezil. Use the plastic spoon that comes with your medicine to measure out your dose. If you do not have a measuring spoon ask a pharmacist for one.

Do not use a kitchen teaspoon as it will not give the right amount. If you forget a dose of donepezil, skip the missed dose and take the next one at the normal time the next day. If you've forgotten to take your donepezil for more than a week, talk to your doctor before you take any more. If you forget doses often, it may help to set an alarm to remind you.

You could also ask a doctor, pharmacist or dementia support group for advice on other ways to help you remember to take your medicine. Get someone else to drive you or call for an ambulance. Side effects are less likely to happen if your doctor starts you on the lower 5mg dose for at least a month.

In rare cases, it's possible to have a serious allergic reaction anaphylaxis to donepezil. These are not all the side effects of donepezil. For a full list see the leaflet inside your medicines packet. You can report any suspected side effect to the UK safety scheme. As your body gets used to donepezil, these side effects should wear off. If you are still bothered by them after a week or two, speak to a doctor. They may want to adjust your dose or recommend a different medicine.

Some medicines do not mix well with donepezil. They can increase the risk of side effects or stop donepezil working as well as it should. Do not take anti-inflammatory painkillers NSAIDs , such as aspirin or ibuprofen, without checking with a doctor first.

St John's wort can lower the levels of donepezil in your blood. This can stop your medicine from working as well as it should. Tell a doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. Donepezil works by helping your nerve cells communicate with each other. It does this by stopping something called acetylcholine from being broken down in your brain. Acetylcholine is an important substance that allows nerves to communicate.

Donepezil does not cure dementia. However, by increasing the amount of acetylcholine in your brain, donepezil can help with symptoms like:. Find out more about how drugs like donepezil work on the Alzheimer's Society website. It usually takes at least a month for donepezil to start to work, but it can take longer for some people.

Donepezil does not help everyone in the same way. Some people find it helps with their symptoms a lot. For others, it might not help at all. You will get a follow-up appointment so your doctor can check how well the medicine is working. They will also check whether you have any side effects. If you are bothered by side effects, tell your doctor. They may be able to recommend a different medicine.

You, or the person you are caring for, will have regular check-ups with a doctor to see whether donepezil is still helping. The effects may wear off a bit 6 to 12 months after you start taking it. Your symptoms may start to gradually get worse again, even if you are still taking donepezil.

The medicine is probably still helping and if you stop taking it your symptoms could become even worse. It can stop your medicine from working as well as it should.

It can also make you more likely to have side effects. Drinking alcohol can also make the symptoms of dementia worse. Authors of this manuscript have nothing to disclose concerning possible financial or personal relationships with commercial entities that may have a direct or indirect interest in the subject matter of the manuscript.

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Subject: Impact of nighttime donepezil administration on sleep in the older adult population: A retrospective study. Sign In or Create an Account. User Tools. Sign In. Skip Nav Destination Article Navigation. Close mobile search navigation Article navigation. Volume 4, Issue 5. Previous Article Next Article. Article Navigation. Research Article September 01 Impact of nighttime donepezil administration on sleep in the older adult population: A retrospective study Carmen Agboton, Pharm.

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Ragan Sweet, Pharm. Mental Health Clinician 4 5 : — Get Permissions. Cite Icon Cite. Alzheimer's disease , donepezil , sleep , night time disturbance. Figure View large Download slide. Search ADS. The safety and tolerability of donepezil in patients with Alzheimer's disease. DOI: Hallucinations and sleep-wake cycle in Alzheimer's disease: a questionnaire-based study in patients.

Therapeutic effect depends on the time of intake]. Moraes Wdos. Pharmacokinetic and pharmacodynamic profile of donepezil HCl following evening administration. Smith Doody.